Database of chemical modifications of DNA found in nature, with detailed information on each one. Includes links to scientific literature describing these modifications and how to sequence them.
I was adopted, and for most of my life all I knew was that my biological parents were English and Irish. A year ago I took a DNA test, and sudden I know a lot more: Who my biological mother was (and the amazing coincidences between our lives), what percentage of my DNA is Neanderthal, and the complexities of Irish identity, ethnicity and genetics.
After five years, the NIH-funded ENCODE Project has unveiled its detailed study of the biochemical context of the human genome. Nature has a special web portal linking together 24 publications in Nature, a special issue of Genome Research, and Genome Biology (all open access). There's also an iPad app to help you navigate through the papers and results. You can look at an enormous poster of results, but it contains only a tiny fraction of the 15 TB of data from the project's >1,600 experiments. Perhaps aerial dance is a better way of portraying what we have learned about genome biology. [more inside]