2 posts tagged with Bacteriophage.
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A Smaller Flea

The purpose of this blog is to share our appreciation for the study of microbial viruses, the viruses that infect Eubacteria (also known as bacteriophage), Archaea, and microbial Eukaryotes. They dominate our planet's ecosystem, serve as a profoundly useful model system for understanding life at its simplest, possess a dizzying array of powerful molecular tools we can borrow, and make steadfastly vicious allies in our fights with problematic microbes. Our name is based on the nursery rhyme "The Siphonaptera," which eloquently describes a beautiful phenomena found more clearly in the viruses that infect microbes than anywhere else.
The Siphonaptera:
Big fleas have little fleas,
Upon their backs to bite 'em,
And little fleas have lesser fleas,
and so, ad infinitum.

And the great fleas, themselves, in turn
Have greater fleas to go on;
While these again have greater still,
And greater still, and so on.
posted by Blasdelb on Sep 19, 2014 - 0 comments

Phage treatment of human infections (PDF)

Phages as bactericidal agents have been employed for 90 years as a means of treating bacterial infections in humans as well as other species, a process known as phage therapy. In this review we explore both the early historical and more modern use of phages to treat human infections. We discuss in particular the little-reviewed French early work, along with the Polish, US, Georgian and Russian historical experiences. We also cover other, more modern examples of phage therapy of humans as differentiated in terms of disease. In addition, we provide discussions of phage safety, other aspects of phage therapy pharmacology, and the idea of phage use as probiotics.
posted by Blasdelb on Oct 30, 2012 - 0 comments

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